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ISSN 1993-4327
© AMI |
2008 № 3
Reviews
Timchenko O.M.
molecular-genetic methods of intraspecific epidemiological typing of
infectious PATHOGEN AGENTS (review)
In Ukrainian
A classification
of methods intraspecific epidemiological genotyping of infectious
pathogen agents is presented. The classification is based on technology
of the methods reproduction, genetic characteristics of
strains,
which are typing, and scope of the use of each
method.
Bondar T.N.
AN
ORGANISM THYROID STATUS AND NITRIC OXIDE
In Russian
Cardiovascular complications at hypo-and hyperthyroidism are connected
with disfunction of vascular endothelium which key regulator is nitric
oxide. Data about sources of synthesis, nitric oxide physiological
effects, mechanisms of regulation of NO-syntases activity are presented.
Possible mechanisms of changes of NO-syntases activity at hypo-and
hyperthyroidism are discussed.
Experimental
articles
Volyansky A.Yu., Nikitchenko J.V., Simirenko
L.L., Kuchma I.Yu., Davidenko M. B.
THE
INFLUENCE OF ALIMENTARY LOAD IN POSTNATAL PERIOD ON THE STATE OF
PROOXIDANT-ANTIOXIDANT SYSTEM OF RAT BLOOD UNDER IMMUNIZATION BY
ADT-ANATOXIN
In Russian
The influence of overnutrition in early postnatal period on the state of
prooxidant-antioxidant system of blood under immunization of Wistar rats
by ADT-anatoxin was investigated. The lowering of reliability of
enzymatic antioxidant system conditioned by the decrease of
selenium-dependent glutathione peroxidase activity was revealed in blood
of experimental animals. It was shown that in the process of formation
of immune response to diphtheria and tetanus anatoxins of ADT-vaccine
the content of enzymatically active ceruloplasmin in experimental rats
was increased at more early stages compared with control rats.
Panchenko L.A., Popova N.G.,
Torianyk I.I., Kazmirchuk V.V.
human herpesvirus Type 6 and ITS infectION level AT THE PATIENTS WITH
laryngopharyngeal DISEASE
In English
High level
of infection with type 6 human herpesvirus (69,2%) was established in
patients with infectious inflammatory diseases of the pharynx and
larynx. Increased level of Ig G antibodies simultaneously to HSV and
HHV-6 was determined in 38,0 % of cases.
Martynov A.V., Chuprinova S.I., Osolodchenko TP.,
Batrak E.A., Zavada N.P.. Ryabova I.S, Shtiker l.G.
INFLUENCE OF THE CHEMICAL ENCHANCERS
COMBINED ACTION ON GROWTH OF MICROBAL MASS OF PSEUDOMONAS AERUGINOSA
In Ukrainian
The chemical
growth factors (enhancers) joint influence is studied on speed of
microbal mass growth of Pseudomonas aeruginosa. Experimentally
well-proven the expressed stimulant influence due to the combined action
of isochinolin’s and imidasol’s derivatives on biological properties of
P. aeruganosa
Yelyseyeva I.V., Babych Ye.M., Zhdamarova L.A.,
Belozersky V.I., Kolpak S.A., Gorbach T.V., Bobireva I.V.
BIOLOGICAL CHARACTERISTICS
OF DIPHTHERIAE PATHOGEN ANTIGENS OBTAINED BY PHYSICOCHEMICAL METHODS
In Ukrainian
Conducted study covers development of approaches to diphtheria vaccine
improvement notably referred to increase of antibacterial immunity as a
factor of diphtheria infection localization in a humane organism.
Physicochemical factors are used for obtaining of native pathogen
antigens. At the first stage of the study the most perspective regime of
the microbe cells ultrasonic disintegration, use of chemical agents and
ultra filtration are taken for antigen preparations obtaining with the
potentially most effective immunogenic and adjuvant properties. A
description of the obtained specimens of antigenic fractions
preparations on chemical composition and molecular weight is
represented.
Babych E.M., Kalinichenko
S.V., Kivva F.V., Volajnskyj Yu.L., Ryzhkova T.A., Kovalenko O.I.,
Zhdamarova L.A., Shkodovska N.Yu., Bobyreva I.V.
THE SENSITINITY OF OPPORTUNISTIC PATHOGENIC
BACTERIA TO DIPHTHERIA TOXIN BEFORE AND AFTER MILLIMETER WAVES
IRRADIATION
In Ukrainian
The growth
kinetics of microorganisms under influence of
the different doses of diphtheria toxin before and after using
millimeters waves determined frequency ranges (40,0 HHz; 42,2 HHz; 50,3
HHz; 58,0 HHz; 61,0 HHz; 64,5 HHz) was studied. It was found
experimentally that after adding diphtheria toxin in nutrient medium in
amount 0,1 ml on 1,0 ml ambiences the growing of S.aureus ATCC 25923
was suspended but the accumulation of E.faecalis ATCC 6783
microbial mass was stimulated. The presence of 0,3 ml diphtheria toxin
in 1,0 ml nutrient medium resulted to enterococcus growth inhibition and
partial S.aureus lysis. It was determined that adding diphtheria
toxin irradiated in different frequency range of millimeter waves in
nutrient medium brought to the differently directed changes in
the growth kinetics of microorganisms which
depended of amount of the toxin, frequencies of millimeter waves and
type used for experiment bacteria.
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