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2006 № 4
Review
Strelnikov L.S., Strilets O.P., Shcherbak E.V.,
Chicitkina V.V., Dolgova T.A.
PERSPECTIVES AND DEVELOPMENT PRODUCTION OF BIOTECHNOLOGICAL DRUGS IN
UKRAINE
In Russian
This article presentation the modern situation and perspectives of
pharmaceutical biotechnology in the world and the Ukraine. In the
article are discussion perspectives applications of biotechnology
methods for production the drugs. Advantage these preparations are low
cost and don’t have any side-effect.
Belozersky V.I., Babich E.M., Volansky Y.L.,
Krasnopolsky Y.M., Chetinina V.M., Kolokolova O.B., Verezub L.G.,
Martinov A.V., Zhdamarova L.A., Sklar N.I., Chuyeshov V.I.
SEXPERIMENTAL APPROACHES TO CREATION OF
ENTERAL FORMS OF ANTIDIPHTHERITIC
PREPARATIONS
In Ukrainian
The data of study of immogenic properties of somatic antigens of
Corynebacterium diphtheria protected by different polymer combinations
at different methods of application are presented. More expressed
immunogenity of liposomal forms of antigen at introduction per os to
experimental animals at background of preliminary parenteral
introduction of this preparation is demonstrated. The conclusion about
the perspective of improvement of immunization shemes with
utilization of effective doses and optimal intervals between the
introduction of preparations.
Volyanskiy A.Y.
THE INFLUENCE OF ADT-ANATOXIN ON
GLUCOCORTICOID STATUS OF RATS OF DIFFERENT
AGE
In Ukrainian
We examined the age-specific glucocorticoid
status characteristics of intact male rats line Wistar aged 3 an 30
months during the immunization with ADT-anatoxin. The age-specific
features of glucocorticoid function GG ACS functional state and the
age-related and specific differences of anti-diptheria and anti-tetanus
antibody genesis during the antitoxic immune response development
process were identified. The empirical mathematical models of body
glucocorticoid status changes in the dynamics of formation process
of the antitoxic immune response are received depending on term after
immunization and age of animals.
Experimental
research
Rijenko S.A., KremenchutskyyG.N., Bredichina
M.O., DiklenkoT.V., Drobot O.V., StepanskyyD.A., ChilkoL.V., Valchuk S.I.,
Urgel L.G., Kondratiev A.U.,
Koshevaya I.P.
TECHNOLOGY OF CREATION OF LIQUID PROBIOTIC
FROM AEROCOCCI
In Ukrainian
The dynamics of growth of culture of
production culture of A.v³r³dans N 167 on different nourishing
environments and an optimum nourishing environment is select for the
receipt of liquid form of probiotics «A-bacterinum». Possibility of
constructing of liquid forms of probiotics is experimentally well-proven
taking into account the biochemical aspects of metabolism of probiotics
cultures and by the observance of principles and requirements FAO/WHO.
On the basis of the received data the basic technological scheme of
manufacture of the liquid form of a probiotic is developed «A-bacterinum».
Smelyanskaya M.V., Peremot S.D., Martynov A.V.
PERSISTENT
HERPESVIRUSES AS POTENTIAL TRIGGER-FACTOR OF SOME SOMATIC DISEASES
In Russian
Obtained results shown that in human’s organism, especially with chronic
somatic pathology, were presented persistent viruses of herpes
group in one or more organs with big probability. Presence persistent
viruses of herpes group in one or more human’s organs can start
mechanism of reactivation of persistent infection, caused by herpes
virus with involved in infectious process other not herpes group
viruses. Besides after infected by herpes virus of host organism
the related virus from other group are possible caused of they
exaltation action.
Mokienko
A. V., Petrenko N. F., Gozhenko A. I., Ponomarenko A.N.
CHLORINE DIOXIDE AS AN AGENT OF PROPHYLAXIS
OF NOSOCOMIAL INFECTION
In Russian
In the work some given literatures on interrelation microbial
contaminations of water and flares of nosocomial infection are
submitted. The necessity of a padding decontamination of water submitted
in hospitals is proved. The assumption of an opportunity of
application for this purpose of chlorine dioxide as high performance
desinfectant is stated.
Astahova
V.S., Panchenko L.M., Golovchanska A.D.
USING OF
CLONING METHODS FOR DISCOVERING THE INFLUENCE OF ENDOGERMETICS ACTION ON
STROMA CELLS (IN VITRO)
In Russian
The results of investigation of cytotoxic influence of materials for
root canals feeling by cells-cultivating method are described in the
article.
Obuchovskaya O.V., Stegniy B.T., Keleberda N.I.,
Glebova K.V.
DEVELOPMENT OF INDIVIDUAL CHARTS OF
APPLICATION OF ANTIBACTERIAL PREPARATIONS AT INFLAMMATORY PATHOLOGIES OF
SKIN AND MUCOUS MEMBRANES FOR DOGS ON BASIS OF RESULTS OF STUDY OF
PROPERTIES OF SELECTED MIKROFLORY
In Russian
During conducting of bacteriological study of pathological material from
dogs with different pathologies (dermatitises, vaginits, postits,
conjunctivitises, otitides and stomatits) isolated and studied 205
cultures of microorganisms. It is set that gram+ cocci (representatives
of births of Staphylococcus, Streptococcus and Micrococcus) and
enterobakterys (representatives of Proteus, Citrobacter and Serratia)
have most etiologic value, which in 81,46 % cases selected in
composition bacterial associations. The sensitiveness of the selected
cultures is studied to the basic groups of antibiotics. Methodical
approaches are certain to development of individual charts of treatment
POSTERS OF RESEARCH-AND-DEVELOPMENT INTERNATIONAL
CONFERENCE "THE SEARCH AND DEVELOPMENT OF THE NEW PREVENTIVE AND
THERAPEUTIC ANTIMICROBIAL AGENTS, ANTISEPTICS, DISINFECTANTS AND
PROBIOTICS" 20-21 NOVEMBER 2006 KHARKOV-2006 |
