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2007 №
3
Review
Krestetska S.L., Nesterenko
A.M.
QS-DEPENDENT VIRULENCE REGULATION IN PSEUDOMONAS AERUGINOSA
In English
The
discovery of the cell-to-cell communication in the bacterial populations
led to the understanding that prokaryotes are capable of coordinated
activity. That facilitates development of a very attractive field of
research, within which exists ability to reveal fundamentally new
patterns that control course of events during bacterial infection, and,
appropriately, preconditions for development of new therapeutical
approaches also exists. For the recent years different kinds of quorum
sensing systems, that support the perception of population quantitative
conditions and ensure its application for synchronisation of the certain
gene expression, were described in different species of microorganisms.
One of the most studied objects is P.aeruginosa. Its adaptive potential
provides the ability to exist in different environmental conditions, to
infect a wide range of the organisms (from Protozoa to Homo sapiens) and
to modulate population behaviour aggressiveness in compliance with its
suitability degree.
Yudin I.P.
MODERN
APPROACHES TO VIABILITY ASSESSMENT OF BACTERIA WITH ACCENT ON
NONCULTURABILITY PHENOMENON
In Russian
Problems of bacteria viability
determination were considered from the point of view of opportunity of
them surviving in a nonculturable state. Traditionally, since appearance
of microbiology as sciences, methods of cultivation were and, by and
large, remain "the gold standard" for bacteriologists. However, demands
to accuracy and reliability at detection of pathogenic bacteriums, to
determination of their viability now have considerably increased.
Kolyada T.I., Brusnik S.V.,
Andreeva I.D., Nesterenko A.M., Sherbak O.N., Mikhailichenko M.S.
SOME FEATURES OF IMMUNE STATUS UNDER
THE IMPACT OF DIFFERENT IONIZING IRRADIATION DOSES
In Russian
Ionizing irradiation causes a
complex profound metabolic impairment of the organism, that affects the
immune system. The variation of irradiation dose and its power, as well
as the influence of irradiation on the part of the organism, leads to
the specific changes of the immunologic manifestations. One of the
leading causes of the immunological impairment is the development of the
thymic function depression, that causes deeper changes in the cellular
im munity compared to the humoral immunity.
Experimental
research
Virology
Panchenko
L.A., Torianik I.I., Popova N.G., Kandzuba S.I., Popova L.A.
DETECTION OF MARKERS OF ACUTE HERPESVIRUS PROCESS, ASSOCIATED WITH
HERPES SIMPLEX AND EPSTEIN-BARR HERPES VIRUSES
IN PATIENTS WITH ACUTE AND
CHRONIC LARYNGITIS
In English
Markers of acute HSV infection (Ig M to
HSV) were detected in the blood of 108 patients, including 47.5 % of
patients with acute and 26.4 5 % of patients with chronic laryngitis.
Acute EBV infection markers (VCA-Ig M and EA-Ig G) were detected in 6
from the 23 (26.6 %) examined patients.
Korniichuk
I, Ustyanenko D., Kot T., Kharina A., Polishuk V.
INFLUENCE OF HETEROPOLYNUCLEAR COORDINATE COMPOUNDS OF METALS AND SALTS
OF HEAVY METALS ON THE DEVELOPMENT OF VIRAL INFECTION IN PLANTS OF
NICOTIANA TABACUM
In Ukrainian
The antiphytoviral activity of
heteropolynuclear compounds of metals Н201, Н399, Н417 and salts of
heavy metals on the model system tobacco mosaic virus (TMV) - Nicotiana
tabacum was studied. The substance H417 showed the largest influence on
the TMV infectivity. It inhibited the infectivity of tobacco mosaic
virus for 40%. While studying the main contents of some complex
substances of heavy metals the activity of NiCl2 × 6H2O was showed. The
substance inhibited the development of callus for 36%.
Kuznetsov S.V., Kirsanova T.A.
IMMUNE STATUS OF CHILDREN WITH ROTAVIRAL
MIXED INFECTION
In Ukrainian
The article presents the results of the study of
cytokine status and immune response of 64 children with rotaviral mixed
infection. Investigation shows that acute period of rotaviral mixed
infection accompanied by reliable increase of interleukines -1b, -4, -6
and tumor necrosis factor a. In early reconvalescence period the level
of these interleukines stays increased. The immune responce of rotaviral
mixed infection is characterized by decreased level of СD3+, СD4+, СD8+
lymphocytes at the background of physiological level of СD14+, increased
level of СD19+ during the whole period of the disease, physiological
level of antibodies A, M, G in acute period and increased level of
antibody G in early reconvalescence period. Mathematically proven fact
is children with rotaviral mixed infection has hypocompensatory variant
of operation of immunity.
Microbiology and immunology
Diachenco V.F.
Mariushchenko A.M., Artiomov Yu.V., Yagniuk Yu.A., Bacumenko A.V.,
Yagniuk A.I., Piatacov A.V.
SPECIES
COMPOCITION AND ANTIBIOTICS SENSIBILITY OF BILES MICROFLORA OF THE
PATIENTS WITH INFLAMMATORY PATOLOGY OF BILIARY TRACT
In Ukrainian
The bacteriocholia has been revealed at 91,3 %
investigated patients with acute and chronic inflammatory diseases of
biliar tract. Species composition of biliar microflora is presented
first of all the enterobacteria and the bacteroides. The major part of
separated from the bile microorganisms was resistant to the antibiotics,
that are used traditionally in surgical practice for the treatment and
prophylaxis of infections complications.
Volyanskiy A.Y., Simirenko L.L., Kuchma I.Y.,
Misin V.V., Nikitchenko Yu.V., Davidenko M.B.
INFLUENCE DIPHTHERIAL AND АDT-ANATOXINS ON АNTIBODYGENESIS AT RATS OF
DIFFERENT AGE
In Ukrainian
Investigated process of formation of the humoral
immune answer on diphtheria and АДT-anatoxin at 3- and 20- month old
male Wistar rats. Fixed, that irrespective of age the immunization by a
diphtherial anatoxin was accompanied by more appreciable level specific
antibodygenesis, than at an animal under influence АDT-anatoxin.
Оsolodchenko Т.P
BIOLOGICAL PROPERTIES OF MICRORGANISMS CULTIVATED ON NUTRITIOUS
MEDIUM RESEIVED FROM INDUSTRY WASTE
In Ukrainian
In work the opportunity use for reception of a
nutritious basis for microbiological nutrient mediums by acid hydrolysis
is shown. The estimation properties of the received nutrient mediums on
the basis of studying process of cultivation microorganisms and
biochemistry properties in comparison with standard nutrient mediums is
given. |
