Scientific Journal "Annalls of Mechnicov's Institute"

 

 

 

 

 

2008 № 2

 

Reviews

Kuznecov A.V., Sidenko V.P., Ponomarenko A.M.
CONCEPTUALLY-ANALYTICAL     ASPECTS       OF ECOLOGY       OF  NATURALLY HEARTHAL ILLNESSES 
In Russian
Analytical researches of ecological essence  of naturally hearthal  illnesses, based on modern information  of epidemiology,  immunology and molecular biology, are pull out conception of origin and existence  of interspecific biocommunications, depending both on pathogenicity and virulence of genome and from symbiotic relations between donors, vections, recipients  and exciters in natural  landscape and water environments. On the stages  of pre-adaptive  processes,   the origin of antigen  variants and population is assumed sensible and receptive to the warm-blooded animals, the natural hearths of dangerous illnesses are formed  in investigation of which  regardless of man. Presented materials in the process of researches and fundamental researches including on territory of international transport corridors suppose allow in future practically to ground authentic essence of ecology of naturally hearthal illnesses.

Yurchenco L.A.
BIOLOGY OF BACTERIA  PROTEUS SPP. AND IT’S  PATHOGENETIC  SIGNIFICANCE

In Ukrainian
The review of the scientific literature representing the modern data on a nature of Proteus spp., its biological properties, antigen's structure, pathogenic factors , and also about interaction Proteus spp. with macroorganismes and his normal microorganismes  is submitted.

Kandzuba S.I.
THE PROBLEM OF THE ETIOPATHOGENESIS  OF THE MIXT MYCOPLASMA-VIRUS INFECTIONS IN THE HUMAN  AND ANIMALS ON  THE CELLULAR AND ORGANISM LEVELS OF INTERACTION
In Russian

The problem of the etiopathogenesis of the mycoplasma-
virus infections  at the human  and animals on cellular and  organism  levels of interaction are presented. Necessity of development of methods of complex diagnostics at patients with mixt-infections is underlined.  It is necessary the development of methods of complex diagnostics at patients with mixt-infections.

Experimental articles

Kolyada T.I., Andreieva I.D., Sherbak O.N., Brusnik S.V., Nesterenko A.M., Mikhailichenko M.S., Kolyada O.N.
CLINICAL AND IMMUNOLOGICAL ASPECTS OF INFECTIOUS MONONUCLEOSIS
In English
The connection between the severity of clinical manifestations and immune response features in patients with acute infectious mononucleosis (IM) was studied. It was established, that in IM patients with minor disease severity dominated the cellular-mediated response. In IM patients with mild disease severity the humoral-oriented immune response predominated. The described above findings suggest the need of differential approach of immune modulators application in IM therapy, depending on the level of disease severity.

Diachenco V.F., Mariushchenko A.M., Yagniuk Yu.A., Isaeva S.J., Bacumenko A.V.,  Yagniuk A.I., Piatacov A.V.
ETIOLOGICAL SPECTRUM OF THE PURULOINFLAMMATORY COMPLICATIONS IN THE MINIINVASIVE SURGERY OF THE RUPTURED ULCER OF DUODENUM
In Ukrainian
The microbiological  spectrum of wounded exudate with patients have after the miniinvasive operations in the abdomen cavity in connection with the ruptured ulcer of the duodenum was founded during the bacteriological researches. The role of aerobic and  anaerobic bacteriums in the origin of puruloinflammatory complications after laparoscopic stitches of the ulcer defect.

Volyanskiy A.Yu., Kuchma I.Yu., Nikitchenko Yu.V., Simirenko L.L.
THE EFFECT OF 1-METHYL-2-MERCAPTOIMIDAZOL INFLUENCE ON THE PROOXIDANT-ANTIOXIDANT SYSTEM IN RAT’S  BLOOD AFTER ADT-IMMUNIZATION
In Russian

The dynamics of lipid hydroperoxide concentration changes, enzymatically ac­tive ceruloplasmin concentration, superoxide dismutase and glutathione peroxidase activities in blood serum of 3-monthly old rats under long-term administration of 1-methyl-2-mercaptoimidazol (mercazolil) and in the process of immunity response formation against diphtheria and tetanus anatoxins of ADT-vaccine was studied. The investigated antithyroid remedy was revealed to displace the prooxidant-antioxidant balance of blood to the side of antioxidants. The ad­ministration of ADT-vaccine against the background of mercazolil had resulted in the slowing of changes of glutathione peroxidase activity and enzymatically active ceruloplasmin content.

Kozar V.V., Kudrya M.Y., Prilutskiy A.S.
THE INFLUENCE OF HIPOESTROGENIA TO THE ANTIBODIES LEVEL TO THE ENDOTOXIN  (EXPERIMENTAL RESEARCH)
In Ukrainian
The hipoestrogenia influence on the endogen intoxication state by the antibodies level to the endotoxin  has been studied. In the experiences on the rats it has been revealed that the female castration was accompanied to the antibodies level to the endotoxin   increasing in blood serum. The decline of the diagnostic index stays on the merely same level that in ovariectomia rats group with extra carbohydrate charge.

Some aspects of biohazard

Martynov A.V.
NOT PLANNED VACCINATION AGAINST MEASLES AND GERMAN MEASLES AS THREAT FOR NATIONAL BIOLOGICAL SAFETY IN UKRAINE (ANALYSIS OF FACTS AND PROGNOSIS OF CONSEQUENCES)
In Ukrainian
Facts which allow to classify a provided the not planned vaccination against a measles and rubella by Indian KK vaccine  in Ukraine in 2008 as an act of biological aggression against the population of Ukraine with the purpose at demographic adjusting for birth-rate level are resulted in the article. It is show that on custom territory of Ukraine it is illegally brought a biological agent from two living viruses, one of which is a measles virus (strain Edmonton-Zagreb) on virulence actually does not differ from the field measles virus, and on ability for replication even with specific antibodies presence in vaccinated human’s blood. In addition, for vaccination was chosen the population category, which is the most vulnerable for these agents with tropic to the genesial organs. It is also indicated on the fact of measles growing in human’s cells culture that contains  chorionic gonadotropin as the main stimulator for cells growth (embryonic serum). The last component (gonadotropin) is the basic component of vaccines for population sterilization , development by WHO and by UNICEF from 1970 years.