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2005 №
2
Review
Volyanskaya N.P., Gritsenko I.S.
ANTIMICROBIC ACTIVITY AND PHARMACOLOGICAL EFFECTS
OF PHENOLIC SUBSTANCE
Article in Russian
The review of a biological potency of
antimicrobic action and pharmacological properties of phenol’s
derivatives is resulted. The prospect of search in series of phenol’s
derivatives effectiveness and nontoxic antimicrobic substances is
certain.
Experimental
research
Babych Е.М., Sklyar N.I., Volyansky Y.L.,
Zhdamarova L.А.,
Belozersky V.І.
MICROBIAL INTERACTIONS OF ANTAGONISTS AND
SYMBIONTS IN RELATION TO HELICOBACTER PYLORI
Article in Ukrainian
The results on determination of character of microbial
interactions of 158 associations isolated from bioptic samples of
gastroduodenal tract in 109 patients with peptic ulcer and
gastroduodenites are presented in this paper. Microorganisms-symbionts
and antagonists in relation to Helicobacter pylori have been determined
which were characterized by both high and low potential of enzyme
activity. Within the group of bacteria which actively inhibited vital
functions of helicobacters there were determined strains which are found
to be competitors as well to the concomitant mucosal microflora with
high potential of enzyme activity and to microorganisms-symbionts for
Helicobacter pylori. The strains isolated are promising for development
of probiotic preparations.
Derkach S.A., Nosatenko A.I., Krylova I.A.,
Gabisheva L.S., Davidenko M.B., Litkevich A.A.
EFFECT OF COMBINED ABIOTIC FACTORS ON VEGETATIVE
PROPERTIES OF Salmonella typhimurium
Article in Ukrainian
The results of the influence of different abiotic factors on the
vitality of the culture of Salmonella typhimurium were
revealed. The role of medium (tap water, water from melted snow),
temperature conditions of cultivation.
Diachenko V.F., Mariushenko A.M., Yahniuk Yu.A.,
Bacumenko A.V.
STUDY OF THE ANTIGENICAL
STRUCTURE OF BACTEROIDES FRAGILIS
Article in Ukrainian
The common polysaccharide antigen of Bacteroides fragilis strains was
investigated. The strains used in this study were: B.fragilis (№ 13/83),
B.fragilis (№323) and recent clinical isolates.The polysaccharide
antigen extracted by aqueous phenol methods. A specific antiserum
against Bacteroides fragilis strains polysaccharide antigen was
prepared. The study indicated that in most strains of Bacteroides
fragilis the common polysaccharide antigen was present.
Kozko I. N., Andrushenko I. N., Belokon I. F.,
Volyanskiy A. Yu., Kazmirchuk V. V., Shulga N. N., Spiridonov A. V,
Povolokina I.V.
TO QUESTION OF INCREASE OF EFFICIENCY OF THE USE
OF ANTIBAСTERIAL FACILITIES AT INTESTINAL INFECTIONS
Article in Russian
Reduction of valid for one occasion dose on the reception
in 1,5 - 2
times antibacterial facilities on the
example of pills of norfloksacyn in combination with the «Polidekanit
granules» rendered the expressed therapeutic effect not different from
an effect in a control group, but considerably lowered the risk of
display of negative influences of antibiotic. The offered combination of
preparations causes complete sanation from pathogenic microorganisms,
having minimum influence on the useful flora of intestine.
Introduction to combination of
preparation with action
enveloping and adsorbent
is accompanied by the considerable increase of specific antibacterial
activity due to deceleration of suction and increase of display of
action of antibiotic on intestinal microflora.
Introduction of the given complex method of the medical
treatment sharp intestinal infections in clinical practice will allow to
decrease side effects, duration of course of medical treatment of
patients, and also expenses on the medicinal providing.
Krasovsky
V.V., Shagun V.G., Timchenko O.M., Pokhil S.I.
IMPROVEMENT
OF THE METHOD OF SANITARY-BACTERIOLOGICAL CONTROL OF THE LEVEL OF
CONTAMINATION OF HABITAT OBJECTS BY LEGIONELLA
Article in Ukrainian
Effect of different selective factors (heating, acid action,
antibiotics, dyes, etc.) on Legionella spp. and on microorganisms of
other taxonomic groups has been studied in experiments with model and
natural water samples. It was concluded that during the
sanitary-bacteriological control of water systems of natural and
man-caused origin to determine their contamination level by Legionella
spp (CFU/ml) in a more precise manner it is necessary to use the
determined correction factor (1 - 2∙104) corresponding to
each selective factor.
Nekhoroshikh Z.N., Malikova M.V., Boschenko Yu. A., Broshkov M.M.,
Shevchuk L.I., Маlceva T.V., Djortubaeva G.N.
PROFESSIONAL
ZOONOSES OF CHLAMYDEOUS ETIOLOGY
Article in Russian
The results of chlamydeous infection spread study in agriculture animals
and in professional contingents are given.
Complex of measures, that is
directed on zoonosis chlamydeousis prophylaxis, is proposed.
Panchenko L., Volyansky U., Kratenko I.,
Gerasujta N., Odraziy N., Toranik I., Korovaeva I., Ilina N.
CHARACTERISTIC OF THE DRIFT-VARIANTS OF INFLUENZA
A VIRUSES, ISOLATED IN DIFFERENT EPIDEMIC YEARS IN KHARKOV
Article in Russian
The drift-variants of influenza a viruses with different antigenic
properties were isolated in the epidemic years in Kharkov. In 1986
influenza А(H3N2) virus was dominanted, which
was isolated on the gallinaceae embryos. In 2003 - А(H1N1)
virus, which was isolated on the cells culture MDSK.
Popov N.N.,
Ovcharenko A.S., Romanova E.A., Volkov T.A.
SITUATION WITH ANTIMICROBIC IMMUNITY OF PATIENTS
WITH COMBINED FORMS OF ENDOMETRIOSIS
Article in
Russian
The examination of
86 patients testify that endometriosis is taking at the background of
disturbed microbiocenosis of the genitals and fall of antimicrobic
immunity. The patients demonstrate low antimicrobic antibodys titres,
its affinity and degree of glycosilation in comparison with healthy
womans.
Romanova E.A., Sidorenko T.A., Igumnova N.I.,
Yuchimenko V.I.
OPTIMIZATION OF HEMOPOIESIS OF ANTENATALY
IRRADIATION POSTERITY OF RATS BY APPLICATION OF CELLULAR
TRANSPLANTATION
Article in
Ukrainian.
The aim of study is influence
of allogenic cellular myelotransplant in the subtransplantation doses
(1,5x104 and 3,0x104 cells) to the hemopoiesis of
rats, which were irradiated in the early embryonic period. It was found
out that less dose of mielocaryocytes was more effective for
normalization of hemopoietic variational parametess. It was shown that
cellular bone marrow transplant may be apple with aim of regulation of
pathologic hemopoiesis.
Sladkova L.M., Rizenko S.A., Stetsenko I.Yu.,
Semenyuk M.V.
ABOUT PROBLEM OF SALMONELLOSIS INFECTION
Article in
Ukrainian.
Deep retrospective
epidemiologic analysis and studing of heteroantigens is caused by high
level of salmonellosis. It has been determined the great meaning of
infections pathology of macroantigens and microorganismus. During
salmonellosis epidemiological process great attention is paid to
antigenic infections excitement. It has been determined deep connection
of correspondence with specific buteroantigen of bacterium polymorphism
according to blood group of patients with salmonellosis.
Sukhodub L.F., Kuchma I.Yu., Sukhodub L.B.,
Volyansky A.Yu.
MODIFICATION
THE STRUCTURE OF HYDROXYAPATITE BY METAL IONS- COMPONENTS OF MEDICAL
IMPLANTS
Article in
Ukrainian.
In the paper
one of the problems connected with an interface “ implant-bones”,
namely, the influence of metal ions-constituents of medical implants on
the hydroxyapatite structure is described.
Tarasyuk O.O., Borys V.M., Kostyk O.P.,
Verbinets A.V., Zarichna O.Z., Golubchenko L.K., Kogut O.M., Purska M.B.,
Vivchar I.S., Zavyalkin V.M., Mudryk G.A.
EPIDEMIC SITUATION WITH
TUBERCULOSIS IN THE LVIV REGION
The epidemic situation with tuberculosis in 20 districts of the Lviv
region for 2000-2004 years are investigated and analysed. The basic
tendencies with tuberculosis in different age groups are determined. The
changes in frame of the forms of a tuberculosis, feature of a
pathomorphism of a tuberculosis in modern conditions are investigated.
The situation with tuberculosis for last 5 years in the Lviv region
remains stable, except for a situation in mountain and foothill
districts. The stability of the revealed tendencies permits to hope on
improvement of epidemic situation as a whole.
Таrasyuk O.O., Shyshka H.V., Маlahov V.К.,
Lomnytska V.B., Prunko Т.D., Dubytskyi I.N., Sydor L.N., Shpataryuk О.V.,
Моtа B.Е.
METHOD OF
CORRECTION OF DISBIOSES OF A LARGE INTESTINE
Article in
Ukrainian.
In conditions
of a chronic intoxication with a mixture of heavy metals with compounds
of suphur the expressed dysbacteriosis of a large intestine develops. In
experiment the expediency of applying of binary medical complexes “
spirulina + lactobacterinum ”, “ spirulina + bacteriophage ” and
three-component medical complex “ spirulina + bacteriophage +
lactobacterinum” for корекции of microecological changes in a large
intestine is demonstrated.
Timchenko O.M., Pokhil S.I.
COMPARATIVE
CHARACTERISTIC OF METHODS FOR DESTRUCTION OF MICROORGANISMS CELLS TO
OBTAIN INTACT FORMS OF PLASMID AND CHROMOSOMAL DNA
Article in
Ukrainian.
To destruct
cells of bacteria from different taxonomic groups with purpose to
isolate chromosomal and plasmid DNA (ChrDNA, PlDNA) there were tested
experimentally seven the most widespread methods: ultrasonic (gaseous
cavitation) disintegration method (USM), guanidinium thiocynate method (GTM),
proteinase K – method (PKM), method of rapid mini-lysis (MRML), method
of alkaline lysis (MAL), method of triton lysis (MTL), method of lysis
in agarose blocks (MLAB). MRML, MTL and MLAB are the most efficacious
(by percent of destructed bacterium cells, free DNA concentration,
integrity level for molecules ChrDNA, PlDNA) for genotyping of
microorganisms strains.
History of
medicine
Pugach N. В.
HISTORICAL AND PHILOSOPHICAL ASPECTS OF
MECHNIKOV`S THEORY ABOUT ORIGINS OF INFECTIONS DISEASES
Article in Russian
In the work the author pays attention to the theoretical and cognitive
aspects. I.I. Mechnikov’s scientific work which are not enough explored.
It is made logical reconstruction of genesis and development of
phagocyte theory, its creative methods. The author investigates some
questions of heuristic function of phagocyte cellular theory of
immunity. Here it is also determined the role of experiment in the
explanation of complicated correlations of pathogenic microbe and human
and animal organism.
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