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Frolov A.F.
The concept of struggle against infection
contaminations at the present stage
Article in Russian
In article the review of the literature concerning a modern state of
struggle against contagions in modern conditions is presented. It is
shown an essential role of persistent viruses in complication of an
epidemic situation in the world recently. Paths of the further struggle
against epidemies of dangerous infection contaminations are offered.
Strategy of behaviour of the state in conditions of threat of modern
epidemies is offered.
Gataullin A.G. Blinkova
L.P., Mihailova N.A., Elkina S.I., Gaiderov A.A.,Kalina N.G., Gorobets
O.B.
Changing of the intestinal microflora
composition as a characteristic of effectiveness after the
administration of medical preparations
Article in Russian
Influence of preparation Cifran by dose 1,5 mg, 5 days, probiotic
B.subtilis by doses 500 x Ю6 and 1 x Ю9 bacteria/mouse, biologically
active additive "Spirulina VEL" by doses 1 mg and 10 mg/mouse in mice
experiments to me large intestine microflora was studied.The total
microorganisms number on nutrient medium with serum was 3-6 x 109 CFU/ml.
The number of lac+/lac" microorganisms S.aureus/Staphylococcus spp.,
Lactobacillus, Bifidobacterium, Enterococcus, Pseudomonas, Candida et
all was changeable according to the applied preparation.
Shmygaleva T.P., Gorobets O.B., Muhin V.A.,
Novikov V.Yu.Blinkova L.P.
The
results of studies on the comparative evaluation of the fermentative
hydrorysates from prawn, king crab, giant scallop, sea-cucumber are
presented as nutrient basis of media
Article in Russian
The dominant level of the protein, leucine, isoleucine for sea-cucumber,
proline for king crab and leucine for giant scallop was shown by
biochemical analysis of hydrolysates. A highest level of microbe biomass
Shigella flexneri la was established after cultivation test strains on
the nutrient agar with hydrolisates from see-cucumber and prawn. The
pigment production of microorganisms was standard excepting media from
the giant scallop basis.The fermentative hydrolysate from giant scallop
was not enough for providing normal growth of S.pyogenes Dick 1 in the
nutrient brouth. Thus, hydrolysate from prawn, king crab and
see-cucumber are suitable for further studying.
Osolodchenko T.P, Nikolaenko V.M., Bozhko M.G.
Working
out methods for transformation waste of gamaglobulin manufacture in form
which accessible for bacteriums
Article in Ukrainian
Receiving regimes of nutrient basis in the way overdoing waste
gamaglobuline manufacture of pancreas which let to get nutrient forms
for microorganisms was worked out. You can see possibility of their
using constructions of nutrient mediums.
Osolodchenko T.P., Pasichnik T.O., Nikolaenko
V.M., Shtiker L.G., Batrak L.A., Zavada N.P., Raybova I.S,.
Working
out nutrient medium for receiving biomass staphylococcus aureus
Article in Ukrainian
Nutrient medium was worked out on basis of acid hydrolysate of active
silt for biomass cultivation Staphylococcus aureus. Nutrient medium
provide enough activity increase and have low prime cost in compare with
prototype.
Plovetska LA.
Features of dynamics of the influenza and acute
respiratory virus infection of the gas-discharge lamps' plant
Article in Ukrainian
The results of own researches are reported. In the Poltava Gas-Discharge
Lamps' Plant, the legibly expressed seasonal regularity of dynamics of
the influenza + ARVI (acute respiratory virus infection) morbidity with
maxima of quantity and general duration of cases in the second half of
winter and minima in the second half of summer is observed. The duration
of a separate case has three almost identical maxima in January, May and
September. The trends of quantity of cases of influenza -ARVI diseases
and general quantity of days of disease indicate existence of the
legible long-term tendency to ascending of these parameters. The mean
duration of one case practically does not change. Dynamics of all
parameters has an the expressed periodic component, which requires
further research, as well as factors conditioning it. Similar researches
on other plants with some harmful working conditions are necessary for
the elucidation of the role of the harmfulness of production.
Torianik I., Panchenko L. A., Kuchma I. Y., Volyansky A. Y.,
Volyansky D.L.,Kazmirchuk V. V. , Radchenko E. А., Popova N. G. ,
Makarenko V.D
Herpes Viral Infection and Structural Changes
in Women's Placenta
Article in English
Placental preparations stained with hematoxylin-eosin and according to
Van Hison were studied by histological method. Typical destructive
vascular lesions with pronounced disorganization of endothelial wall,
signs of stasis and thrombosis in 8 preparation of placenta were
established in morphological investigations. In placental emulsions with
the help of immunofermental method Herpes simplex virus of the 1-st type
was detected.
Smelianskaya M.V.Voliansky J.L., Peremot S.D.,
Shmatko S.А.
Features immunity at children sick of the tuberculosis and
citomegalovirus infection
Article in Russian
At children sick combination of infections – TBC+CMV-, it is marked
antigen induced immunosupressis, caused persistentnia CMV, which the
immune inflammation against itself (specific immunosupressis) and
nonspecific against micobacteria tuberculosis (nonspecific
immunosupressis) specifically brakes. It is necessary for taking into
account at carrying out immunorehabilitation of patients with a
tuberculosis
Ryzhenko S.A.
Antagonistic activity probiotics in respect of
microorganism Dnepropetrovskaya regional sanitary-epydemiological
station
Article in Ukrainian
The results of research of antagonistic action probiotics Colibacterinum,
Bificol, Bifidumbacterinum, Lactobacterinum, Linex, Biosporinum and
A-bacterinum on conditional – pathogenics microorganisms resistance
antibiotics, C.albicans and N.meningitidis are submitted.The various
antagonistic activity probiotics is fixed concerning investigated
microorganisms from absence her up to expressed. The marked antagonistic
action probiotics it needs the further study for possibility application
them in complex therapy of diseases caused resistance strains of
microorganisms, and also for study epidemic strains as an
epidemiological marker
Chernyavsky V.I.,Biryukova
S.V., Martinov A.V., Smelyanskaya M.V., Belyaevskaya S.Y., Peremot S.D.,
Krivoruchko I.A., Romanova M.V., Radchenko A.A., Saydametov R.R.
Role of helicobacter pylori-herpesviridae association in
ethyopathogenesis of neoplastic injuries of stomach. modern aspects of
study
Article in Russian
Modern aspects of ethyological role of Helicobacter pylori and some
representatives of Herpesviridae family in development of malignant
tumors of stomach are reviewed. The data from literature about potential
action of Helicobacter pylori during of development of MALT-lymphoma and
carcinoma of stomach and relation this pathology with genetic profile of
pathogenesis and his possible role in disorder of optimal relationship
of the processes of proliferation and apoptosis are presented. The
possible role of bacterial-viral association (Helicobacter
pylori-Herpesviridae) in induction of malignant transformation of cells
gastroduodenal zone and their mutual potentially influence on this
process is discussed.
Korovaeva I.V.,Vovk S.I.,
Panchenko L.A.
New coronavirus – etiologic agent of atypical
pneumonia
Article in Russian
The atypical pneumonia, which is causing by new coronavirus, has been
viewed in this article. The data of etiology, epidemiology, clinic
manifestation, diagnostics, treatment and prophylaxis of disease has
been description
Kolotova T.Yu.
Association between transcription and
double-strand breaks formation during high molecular weight DNA
fragmentation
Article in Russian
In this work the results of study of DNA cleavage into high molecular
weight fragments in murine thymocytes and human lymphoblastoma cells (line
CEM) have been summarised. It has been revealed the influence of
inhibitors of RNA and protein synthesis actinomycin D and cyclogeximid
on the high molecular weight DNA fragmentation. The inhibition of high
molecular weight fragmentation in thymocytes by actinomycin D confirmed
the supposition about the requirement of transcription for the DNA
disintegration. Moreover the distribution pattern of topological domains
containing c-myc between cleavable and uncleavable DNA fraction in CEM
cell during and after starvation reflects the transcriptional activity
of the gene.
Dyachenko A.G.,Rudenko C.C.,
Galushko S.S., Bozho M.G., Dyachenko P.A., Pasechnik T.O.
Biological properties of Shigella spp. isolated
in Sumy region in 1996-2003
Article in Russian
The purpose of the study – to determine the sensitivity of Shigella
sonnei and Shigella flexneri to antimicrobial drugs and their clinical
effectiveness for moderating recommendations for empiric therapy of
shigellosis. A total of 164 strains of S.flexneri and 80 strains of
S.sonnei isolated in Sumy region of Ukraine during 1996-2003 years were
tested to 19 antimicrobials: ampicillin (Am), tetracyclin (Te),
rifampicine (Ri), chloramphenicol (Ca), streptomycin (St), fusidin (Fu),
кanamycin (Кn), erythromycin (Er), carbenicillin (Cb), doxicyclin (Do),
gentamycine (Ge), ofloxacin (Of), cefazolin (Cf), ciprofloxacin (Cp).
High rate of resistance were found in both S.flexneri and S.sonnei to:
Am (100%), Te (100%), Cb (90 and 50% respectively), Do (90 and 35%
respectively), Fu (100%), Er (100%), Ri (100%), Ca (71,8 and 45%
respectively), St (81 and 40% respectively). Some isolates were
resistant to ftorchinolones.
36 Shigella spp., sensitivity to antibiotics
Derkach S.A.,Nosatenko
A.Y.,Krilova I.A.,Strogaya E.I., Davidenko M.B.
Some reasons of formation intestinal
dysbacteriosis at children under 3 age
Article in Russian
The reasons of formation dysbacteriosis’s formation at 160 children
under 3 age were investigated. Such factors as alimentary diarrheae,
colitises; allergic diseases (diathesises, dermatiteses); eating of
motherly milk, physiological labor or delivery by cesarean section were
taken into account. Anamnestic data and results of bacteriological
examination were analyzed.
It was established that at 61,1 - 88,6 % of children after delivery by
cesarean section and eating of motherly milk less 25 days had
significant quantitative and qualitative changes in the content of
intestinal microflora. The principal disorders were: decrease of bifidum
and lactobacteria (< 1x107 CFU/g); bacterial contamination; colonization
of enterobacteria, pathogenic staphylococcus wither hemolytic properties,
fungi of Candida genus. Intestinal dysbacteriosis was registrated more
often at children with allergic diseases and with functional disorder of
intestinal tract (33,3 % and 62,5 % of total number of examinated
children, respectively. Such children consist the group of risk, which
needs in examination of intestinal microflora to determine the complex
approach to treatment and choice of optimal probiotics.
Nikolenko Yu. I., Zhadinsky
N.V., Blagoveshchenskaya I. N., Yelskiy V. N.
Nikolay Nikolaevich Blagoveshchensky –
organizer and founder the microbiology department of the Donetsk State
Medical University
Article in Russian
On this article is given the descriphtion of life and a contribution to
the medical science of a famous scientist, the professor Nikolay
Nikolaevich Blagoveshchensky (the founder and the 1 st head of
microbiology department of Donetsk Medical Institute ( hou University),
who was the victim of Stalin terror in the last century.The memory about
Blagoveshchensky is Kept in the works of hes students and followers.
Following his example the up-bringing of the future doctors and
scientists is held at the university.
Kalinichenko S.V.
Influence
of electromagnetic fields on microorganisms
Article in Ukrainian
The modern characteristics of
the electromagnetic fields (EMF) in dependence on the diapasons are
presented in the review. The list of the changeability of biological
properties of the microbes, with undergone to action of different EMF,
is adduced. The possible mechanisms of these physical factories
influence on biological objects are presented. However, in spite of
numerous publications, many questions remain unsolved. There fore, to
our mind, the under stinging of the EMF role of in the process of
microbial changeability and heterogeneity’s formation of circulating
microbial populations of causative agents of the infections is very
important.
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